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D. Tamkosch, M.A., M.D.
Vice Chair, Lincoln Memorial University DeBusk College of Osteopathic Medicine
Reversible prolongation of motor conduction time after transcranial magnetic brain stimulation after neurogenic claudication in spinal stenosis. Comparison of effectiveness according to different approaches of epidural steroid injection in lumbosacral herniated disk and spinal stenosis. Factors influencing the outcome of operative treatment for lumbar spinal stenosis. Correlative study on findings of dynamic myelography and surgical operation in non-bony lumbar spinal canal stenosis. A comparison between two physical therapy treatment programs for patients with lumbar spinal stenosis: a randomized clinical trial. Surgery reduced pain and disability in lumbar spinal stenosis better than nonoperative treatment. Comprehensive review of therapeutic interventions in managing chronic spinal pain. Comprehensive evidence-based guidelines for interventional techniques in the management of chronic spinal pain. Preliminary results of a randomized, equivalence trial of fluoroscopic caudal epidural injections in managing chronic low back pain: Part 4-Spinal stenosis. Unilateral laminectomy for bilateral decompression of lumbar spinal stenosis: a prospective comparative study with conservatively treated patients. The efficacy of prostaglandin E1 derivative in patients with lumbar spinal stenosis. Spinal stenosis in grade I degenerative lumbar spondylolisthesis: a comparative study of outcomes following laminoplasty and laminectomy with instrumented spinal fusion. RefeRences this clinical guideline should not be construed as including all proper methods of care or excluding or other acceptable methods of care reasonably directed to obtaining the same results. Clinical and roentgenographic results of decompression for lumbar spinal stenosis. Cervical and lumbar spinal stenosis associated with myelopathy and cauda equina syndrome. Prolonged relief of pain by brief, intense transcutaneous somatic nerve stimulation. Evaluation of low back pain and assessment of lumbar corsets with and without back supports. Neurogenic intermittent claudication in lumbar spinal canal stenosis: the clinical relationship between the local pressure of the intervertebral foramen and the clinical findings in lumbar spinal canal stenosis. Long-term roentgenographic 97 and functional changes in patients who were treated with wide fenestration for central lumbar stenosis. Midterm results of prostaglandin E1 treatment in patients with lumbar spinal canal stenosis accompanied by intermittent claudication. Therapeutic efficacy of selective nerve root blocks in the treatment of lumbar radicular leg pain. Instrumented versus non-instrumented fusion in surgical treatment of lumbar spinal stenosis: A prospective randomized clinical trial. The efficacy of corticosteroids in periradicular infiltration for chronic radicular pain: a randomized, double-blind, controlled trial. Long-term results of microsurgical treatment of lumbar spinal stenosis by unilateral laminotomy for bilateral decompression. The effect of laminectomy on instability in the management of degenerative lumbar stenosis surgery: A retrospective radiographic assessment. The relationship between the cross-sectional area of the cauda equina and the preoperative symptoms in central lumbar spinal stenosis. Loading is more effective than posture in lumbar spinal stenosis: a study with a treadmill equipment. Mid-term and long-term follow-up data after placement of the Graf stabilization system for lumbar degenerative disorders. The ultimate judgment regarding any specific procedure or treatment is to be made by the physician and patient in light of all circumstances presented by the patient and the needs and resources particular to the locality or institution RefeRences 98 depressants on lumbar spinal stenosis.
Effect of experimental rhinovirus 39 infection on the nasal response to histamine and cold air challenges in allergic and nonallergic subjects. Generic health measurement: past accomplishments and a measurement paradigm for the 21st century. Significance of discoloration in the lower orbitopalpebral grooves in allergic children (allergic shiners). Evaluation of nasal patency: comparison of patient and clinician assessments with rhinomanometry. The association of subjective nasal patency with peak inspiratory nasal flow in a large healthy population. Nasal cytology in allergic processes and other syndromes caused by hyperreactivity. Nasal cytology in rhinitis children: comparison between brushing and blowing the nose. Validity and reproducibility of morphologic analysis of nasal secretions obtained using ultrasonic nebulization of hypertonic solution. Nasal biopsy is superior to nasal smear for finding eosinophils in nonallergic rhinitis. Prevalence and prediction of allergic rhinitis using questionnaire and nasal smear examination in schoolchildren. Correlation of immunoglobulin E, eosinophil cationic protein, and eosinophil count with the severity of childhood perennial allergic rhinitis. Nasal eosinophilic inflammation contributes to bronchial hyperresponsiveness in patients with allergic rhinitis. Macroscopic purulence, leukocyte counts, and bacterial morphotypes in relation to culture findings for sinus secretions in acute maxillary sinusitis. Differences in the spatial distribution of airborne pollen concentrations at different urban locations within a city. Aeroallergen prevalence in the northern New Jersey-New York City metropolitan area: a 15-year summary. Short-term effects of airborne pollen on the risk of allergic rhinoconjunctivitis. Selective expression of a major allergen and cytotoxin, Asp f I, in Aspergillus fumigatus: implications for the immunopathogenesis of Aspergillus-related diseases. Aspergillus fumigatus: identification of 16, 18, and 45 kd antigens recognized by human IgG and IgE antibodies and murine monoclonal antibodies. Quantitation of the major fungal allergens, Alt a 1 and Asp f 1, in commercial allergenic products. Challenges associated with indoor moulds: health effects, immune response and exposure assessment. Temporal associations between daily counts of fungal spores and asthma exacerbations. Allergic alveolitis caused by home humidifiers: unusual clinical features and electron microscopic findings. Localization of a major allergen, Der p 2, in the gut and faecal pellets of Dermatophagoides pteronyssinus. Effect of floorcovering construction on content and vertical distribution of house dust mite allergen, Der p I. Modern prevalence of insect sensitization in rural asthma and allergic rhinitis patients. IgE antibodies reactive with silverfish, cockroach and chironomid are frequently found in mite-positive allergic patients. Spider mite allergy in apple-cultivating farmers: European red mite (Panonychus ulmi) and two-spotted spider mite (Tetranychus urticae) may be important allergens in the development of work-related asthma and rhinitis symptoms. Ladybug hypersensitivity among residents of homes infested with ladybugs in Kentucky. Cat (Fel d I), dog (Can f I), and cockroach allergens in homes of asthmatic children from three climatic zones in Sweden. Safety of antihistamines in the treatment of allergic rhinitis in elderly patients. An investigation into the effects of cetirizine on cognitive function and psychomotor performance in healthy volunteers. Meta-analysis of the efficacy of ebastine 20 mg compared to loratadine 10 mg and placebo in the symptomatic treatment of seasonal allergic rhinitis.
Metoclopramide has been used for decades in veterinary medicine and is an effective anti-emetic. A recent study revealed that the use of maropitant citratee for five days following doxorubicin administration significantly decreased the amount and intensity of vomiting. Some advocate the addition of an H2 blocker (famotidine) or proton pump inhibitor (omeprazole) to minimize the risks of vomiting and reflux esophagitis. Diarrhea following chemotherapy administration has also been reported and is often easily managed with metronidazole or opiate antidiarrheals, such as loperamide. Anorexia attributed to chemotherapy has been reported in oncology patients as well. The most common cause of anorexia is nausea, but occasionally another underlying disease process may be responsible for gastrointestinal signs and should be considered. Some veterinarians will dispense medications for owners to have at home and use on an as-needed basis, for example the ``3-Ms' of maropitant citratee (or metoclopramide), metronidazole, and mirtazapine. Some clinicians, on the other hand, prescribe medications only at the occurrence of clinical signs. In most cases, clinical side effects of chemotherapy are self-limiting or can be managed with owner-administered medications. In some cases, they are life threatening and require hospitalization for more intensive treatment. It may be beneficial to consult a veterinary nutritionist who can formulate a diet specific to the patient. Pain in these patients may be due to the cancer itself, a treatment modality being used. Practitioners have at their disposal comprehensive sources of information on pain management. The linear accelerator is the standard device for administering radiation therapy, and functions by accelerating electrons at relativistic speeds. Goals of Radiation Therapy the goal of definitive or curative radiation therapy is eradication of all viable tumor cells within the patient. Its intent is to cure the patient whenever possible and to prolong survival as long as possible. Most palliative protocols Nutrition the nutritional status of all oncology patients should be routinely assessed beginning at diagnosis and throughout treatment. It is characterized by a distinct set of metabolic changes that are nearly impossible to reverse once they are present, although dietary modifications can slow progression. Diets should be tailored to each individual taking into account their cancer diagnosis, any other disease processes. The most important dietary consideration for canine and feline oncology patients is that the ration is palatable and eaten, otherwise it has no benefit. Providing a complete and balanced diet, whether commercially available or homemade, is imperative. A variety of diets have been used for Pet Radiation Therapy Centers Pet radiology centers are available to veterinarians who wish to refer their oncology patients for radiotherapy. In addition to other resources, the Veterinary Cancer Society provides an online list (vetcancersociety. Preoperative radiation therapy has potential advantages over postoperative radiation. These include treatment of well oxygenated tissue rather than scars, decreased tumor seeding, a smaller treatment volume, and, in some situations, less aggressive surgery. Potential disadvantages include increased wound complications and delayed surgical extirpation. The decision to do so is based on tumor location, surgeon preference, and risk of wound complication. Specifically, canine and feline lymphoma, sarcomas, and carcinomas of the nasal cavity respond favorably to radiation. Canine oral tumors, specifically acanthomatous epulis, squamous cell carcinoma, fibrosarcoma, and melanoma, respond to radiation. Canine soft tissue sarcomas, lymphoma, mast cell tumors, ceruminous gland tumors, thyroid carcinomas, bladder tumors, prostate tumors, perianal adenomas, and apocrine gland anal sac adenocarcinomas also respond to radiation, as does localized lymphoma.
The prevalence of allergic disease and IgE antibodies to house dust mite in schoolchildren in Taiwan. Day-care attendance and increased risk for respiratory and allergic symptoms in preschool age. Does a higher number of siblings protect against the development of allergy and asthma Atopy, asthma, and experimental approaches based on the linear model of cell maturation. The increased prevalence of allergy and the hygiene hypothesis: missing immune deviation, reduced immune suppression, or both Recurrent childhood upper respiratory tract infections do not reduce the risk of adult atopic disease. Prevalence of rhinitis, pillow type and past and present ownership of furred pets. Certain aspects of allergy in children: a critical review of the recent literature. The influx of inflammatory cells into nasal washings during the late response to antigen challenge: effect of systemic steroid pretreatment. Effect of beclomethasone dipropionate on nasal metachromatic cell sub-populations. Inhibition of mediator release in allergic rhinitis by pretreatment with topical glucocorticosteroids. Effectiveness and safety of fexofenadine, a new nonsedating H1-receptor antagonist, in the treatment of fall allergies. Montelukast improves symptoms of seasonal allergic rhinitis over a 4-week treatment period. Randomized controlled trial evaluating the clinical benefit of montelukast for treating spring seasonal allergic rhinitis. Montelukast for treating seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial performed in the spring. Fluticasone furoate nasal spray: a single treatment option for the symptoms of seasonal allergic rhinitis. Optimal dose selection of fluticasone furoate nasal spray for the treatment of seasonal allergic rhinitis in adults and adolescents. Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis. The efficacy of intranasal fluticasone propionate in the relief of ocular symptoms associated with seasonal allergic rhinitis. The role of antileukotriene therapy in seasonal allergic rhinitis: a systematic review of randomized trials. Comparison of intranasal corticosteroids and antihistamines in allergic rhinitis: a review of randomized, controlled trials. Intranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis: systematic review of randomised controlled trials. Tolerance and absence of rebound vasodilation following topical ocular decongestant usage. Effects of Vasocon-A in the allergen challenge model of acute allergic conjunctivitis. Treatment of ragweed allergic conjunctivitis with 2% cromolyn solution in unit doses. The conjunctival provocation test model of ocular allergy: utility for assessment of an ocular corticosteroid, loteprednol etabonate. A randomized, double-masked, placebo-controlled parallel study of loteprednol etabonate 0. A controlled evaluation of the efficacy and safety of loteprednol etabonate in the prophylactic treatment of seasonal allergic conjunctivitis. Capsaicin and nicotine-sensitive afferent neurones and nasal secretion in healthy human volunteers and in patients with vasomotor rhinitis. Chlorine inhalation produces nasal airflow limitation in allergic rhinitic subjects without evidence of neuropeptide release. Exercise-induced rhinitis: a common disorder that adversely affects allergic and nonallergic athletes.