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Team Member Responsible Assessment Intervention Rationale Expected Outcome Activities of Daily Living Nurse Assess respiratory rate every 15 min. Report increase in rate, retractions, or development of nasal flaring or grunting. Increases in respiratory rate and retractions, accompanied by nasal flaring and grunting, may indicate respiratory distress. Exposure to cold increases metabolic rate, increasing need for oxygen and a higher respiratory rate. Parents visit with consultant if desired; state they understand the prognosis for port-wine lesions. Position newborn on her side with head slightly lower than body; suction mouth and then nose with bulb syringe as indicated. Infant appears comfortable in chosen position; need for suctioning becomes infrequent. Assist mother with breast-feeding as needed; remind her that rapid respirations make sucking difficult. Breast milk is the preferred milk for human newborns; a mother may need assistance if an infant sucks poorly. Infant and mother establish mutually enjoyable breast-feeding by hospital discharge. Patient/Family Education Nurse/ Physician Review with parents what were their expectations of new child (bigger? Explain that the presence of a birthmark, rapid respirations, and smaller than expected size are normal variations of newborns. Pointing out positive areas helps parents focus attention on the unique and special qualities of their child. Parents state they appreciate learning more about their newborn from health care professionals. Discharge Planning Nurse Assess whether parents have made plans for hospital discharge. This assessment may be the responsibility of the delivering physician, nurse practitioner, nurse-midwife, pediatrician, or nurse. This health assessment is done quickly, to prevent overexposing the newborn, yet not so swiftly that important findings are overlooked. Height and Weight Assuming newborns are breathing well, they are weighed nude and without a blanket immediately after birth in the birthing room. Measurements such as body length and head, chest, and abdominal circumferences can be obtained in a newborn or transitional nursery. Performing these measurements while an infant is still damp only exposes the newborn unnecessarily to chilling. Newborn weight helps to determine maturity and establishes a baseline against which other weights can be compared. An infant is weighed nude once a day, at approximately the same time every day, during a hospital or birthing center stay. Compare the weight obtained each day with that of the preceding day to be certain an infant is not losing more than the normal physiologic amount (5% to 10% of birthweight). Abnormal loss of weight may be the first indication that a newborn has an inborn error of metabolism, such as adrenogenital syndrome (salt-dumping type), or is becoming dehydrated. Failure to pass nasogastric tube through nares on either side establishes choanal atresia. With excess of 20 mL of fluid, or yellow fluid, duodenal or ileal atresia is suspected. The presence of one artery suggests possible congenital urinary or cardiac anomalies or chromosomal trisomy (if other portions of examination are consistent). Laboratory Studies After the first hour of undisturbed rest, depending on health agency policy, newborns may have heel-stick tests for hematocrit, hemoglobin, and hypoglycemia determinations. Heel-sticks require a minimum of blood, and, although not pain free, they cause minimal trauma to a baby. In some settings, these tests are not routine but are reserved only for newborns with symptoms of anemia, polycythemia, or hypoglycemia.

Dopamine is an endogenous catecholamine that is released into the circulation and acts by binding to 1 receptors as well as to specific dopamine receptors in the renal, mesenteric, coronary, and intracerebral vascular beds, causing vasodilation. It has effects that change with increasing doses by binding to different receptors. At low serum concentrations, dopamine binds to dopaminergic receptors in the renal and splanchnic beds leading to increased urine output and natriuresis. At modest concentrations, dopamine binds to cardiac 1-adrenergic receptors leading to increased myocardial contractility and increased heart rate. At high doses, dopamine binds to -adrenergic receptors and causes an increase in blood pressure and peripheral vascular resistance. Dopamine is an effective agent in increasing blood pressure in hypotensive patients with adequate fluid resuscitation. Dobutamine is a synthetic catecholamine that predominately binds to -adrenergic receptors and enhances myocardial contractility with minimal changes in heart rate. It is often used in treatment of cardiogenic shock following myocardial infarction to support myocardial contractility while reducing peripheral resistance. Phenylephrine is a pure -agonist and its use results in increased peripheral vascular resistance and blood pressure. The increase in afterload increases left ventricular work and oxygen demand, and may cause a decrease in stroke volume and cardiac output. Continuous infusions of nitroprusside require monitoring of serum thiocyanate levels and arterial pH for cyanide toxicity. It is an effective treatment for myocardial ischemia because it diminishes myocardial oxygen demand by reducing excessive preload and ventricular end-diastolic pressure. She recently underwent an uncomplicated left hemicolectomy for diverticular disease. For the first 6 hours following a long and difficult surgical repair of a 7-cm abdominal aortic aneurysm, a 70-year-old man has a total urinary output of 25 mL since the operation. Which of the following is the most appropriate diagnostic test to evaluate the cause of his oliguria? A 72-year-old man undergoes an aortobifemoral graft for symptomatic aortoiliac occlusive disease. Twenty-four hours after surgery the patient has abdominal distention, fever, and bloody diarrhea. A 25-year-old woman presents to the emergency room complaining of redness and pain in her right foot up to the level of the midcalf. She reports that her right lower extremity has been swollen for at least 15 years, but her left leg has been normal. A 76-year-old woman presents with acute onset of persistent back pain and hypotension. Three days after surgery she complains of abdominal pain and bloody mucus per rectum. Which of the following is the most frequent and lethal complication of this condition? A 75-year-old man is found by his internist to have an asymptomatic carotid bruit. Angioplasty of the carotid lesion followed by carotid endarterectomy if the angioplasty is unsuccessful d. Medical risk factor management and carotid endarterectomy if neurologic symptoms develop 421. A 55-year-old man with recent onset of atrial fibrillation presents with a cold, numb, pulseless left lower extremity. He is immediately taken to the operating room for an embolectomy of the left popliteal artery. A 58-year-old man presents with pain in the left leg after walking more than one block that is relieved with rest. On physical examination, distal pulses are not palpable in the left foot and there is dry gangrene on the tip of his left fifth toe.

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Featuresare: · Lyme disease this disease, caused by the spirochaete Borrelia burgdorferi,wasfirstrecognisedin1975inaclusterofchil drenwitharthritisinLyme,Connecticut. Infections occur most commonly in the summer monthsinsusceptiblepersonsinruralsettings. Rationale behind the immunisation programme Diphtheria ­ infection causes local disease with membrane formation affecting the nose, pharynx or larynxorsystemicdiseasewithmyocarditisandneuro logical manifestations. Haemophilus influenzae type b ­ causes invasive disease in young children the number of reports of infection dropped dramatically after the introduction ofHibvaccination(Fig. This was managed with a Hib catchup programme, and to prevent a further resur gence,aHibboosterdosehasbeenintroducedat12 monthsofage. Poliovirus infection ­ Although most infected chil dren are asymptomatic or have a mild illness, some developasepticmeningitisand<1%developparalytic polio. Prior to this, about 530 children under 2 years of age developed invasivepneumococcaldiseaseinEnglandandWales eachyear. Developing countries ­ huge effort and funds are devoted to improving immunisation uptake and programmes. However, public Complications and contraindications Followingvaccination,theremaybeswellinganddis comfort at the injection site and a mild fever and malaise. Some vaccines, such as measles and rubella, may be followed by a mild form of the disease 7­10 1 Infection and immunity 267 2 14 Infection and immunity confidence in the immunisation programme was damaged,anduptakeratesdropped(Fig. Antibody (humoral; B cells) Immunoglobulins IgG subclasses (in children >2 years) Specific antibody responses. There maybeafamilyhistoryofparentalconsanguinityand unexplained death, particularly in boys. Patient-centred screening for primary immunodeficiency: a multi-stage diagnostic protocol designed for non-immunologists. Heterogeneous group of inherited disorders of profoundly defective cellular and humoral immunity. DiGeorge ­ with maldevelopment of the 5th branchial arch causing heart defects, palatal and facial defects, absence of thymus and hypocalcaemia (deletion of section of chromosome 22). Duncan syndrome (X-linked lymphoproliferative disease) ­ inability to make a normal response to Epstein­Barr virus; either succumb to the initial infection or develop secondary lymphoma (X-linked). B-cell (antibody) defects In first 2 years (beyond infancy because of passively acquired maternal antibody) ­ severe bacterial infections, especially ear, sinus, pulmonary and skin infections; recurrent diarrhoea and failure to thrive. Recurrent pneumonias can lead to bronchiectasis; recurrent ear infections to impaired hearing. Recurrent bacterial infections ­ abscesses (skin, lymph nodes, lung, liver, spleen, bone), poor wound healing, perianal disease and periodontal infections; invasive fungal infections, such as aspergillosis. Hyper IgM syndrome ­ B cells produce IgM but prevented from switching to IgG and IgA. Chronic granulomatous disease ­ most are X-linked recessive, some autosomal recessive. Defect in phagocytosis as fail to produce superoxide after ingestion of micro-organisms. Leucocyte function defects Delayed separation of umbilical cord, delayed wound healing, chronic skin ulcers and deep-seated infections. Recurrent meningococcal infections ­ with deficiency of the terminal complement components (C5b to C9). Websites for updates on immunisation and current information on infectious diseases (Accessed May 2011) Meningitis Research Foundation: Available at: Onlyafewstimuliaccountformostallergicdisease: · Paediatric allergy Allergic diseases which affect children include food allergy, eczema, allergic rhinitis and conjunctivitis, asthma, urticaria, insect sting hypersensitivity and anaphylaxis. Proteinswithanunstabletertiarystructuremayberen dered nonallergenic by heat degradation or other forms of processing. For example, some children are allergictorawapples,butcantolerateeatingcooked apples. Mechanisms of allergic disease Many genes have been linked to the development of allergicdisease.

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Moving beyond a single perfusion threshold to define penumbra: a novel probabilistic mismatch definition. The quality of prehospital ischemic stroke care: compliance with guidelines and impact on in-hospital stroke response. Effects of aspirin on risk and severity of early recurrent stroke after transient ischaemic attack and ischaemic stroke: time-course analysis of randomised trials. A systematic review of stroke recognition instruments in hospital and prehospital settings. Endovascular therapy for acute ischemic stroke with occlusion of the middle cerebral artery M2 segment. Effect of conscious sedation vs general anesthesia on early neurological improvement among patients with ischemic stroke undergoing endovascular thrombectomy: a randomized clinical trial. Validity of acute stroke lesion volume estimation by diffusionweighted imaging-Alberta stroke program early computed tomographic score depends on lesion location in 496 patients with middle cerebral artery stroke. Early decompressive craniectomy for malignant cerebral infarction: meta-analysis and clinical decision algorithm. Impact of collateral status evaluated by dynamic computed tomographic angiography on clinical outcome in patients with ischemic stroke. Low-molecular-weight heparin and early neurologic deterioration in acute stroke caused by large artery occlusive disease. Blood pressure reduction in the acute phase of an ischemic stroke does not improve short- or long-term dependency or mortality: a meta-analysis of current literature. General Supportive Care and Treatment of Acute Complications What cardiac monitoring should be done for ischemic stroke patients? Evidence-based guidelines may recommend the use of shared decision-making for decisions in instances where the evidence is equivocal, when patient action or inaction (such as medication adherence or lifestyle changes) can impact the potential outcome, or when the evidence does not indicate a single best recommendation. It is ideal to involve caregivers and family members in these conversations, as well. Family members and caregivers can participate in discussions, ask questions, hear content the patient may miss and provide invaluable support in decision follow-through. Although only patients and clinicians are specifically mentioned throughout this document for brevity purposes, this does not diminish the importance of caregivers and families in patient-centered care. Decision aids can be supportive of this conversation when they communicate the best available evidence to inform the patient and clinician discussion. Without a conversation, clinicians may make assumptions about what the patient prefers. Difficulty in initiating a conversation is cited by patients and clinicians as one of the barriers to shared decision-making. These skills need to be used artfully to address all aspects of the person involved in making a decision: cognitive, affective, social and spiritual. The clinician should use their own words rather than just parroting what they heard. Reflection of feelings usually can be done effectively once trust has been established. This assists the patient in gaining a broader understanding of the situation rather than getting mired down in the details. The most effective times to do this are midway through and at the end of the conversation. An example of this is "You and your family have read the information together, discussed the pros and cons, but are having a hard time making a decision because of the risks. Questioning Skills Diagnosis and Initial Treatment of Ischemic Stroke Eleventh Edition/December 2016 Open and closed questions are both used, with the emphasis on open questions. Verbal tracking, referring back to a topic the patient mentioned earlier, is an important foundational skill (Ivey & Bradford-Ivey). Information-Giving Skills Providing information and providing feedback are two methods of information giving. Information giving allows a clinician to supplement his or her knowledge and helps to keep the conversation patient centered.